Adaptive Immunity: Specific Defenses of the Host |
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Innate (nonspecific) Resistance (Native Immunity) - the genetically predetermined resistance to certain diseases
Factors Affecting Resistance:
Adaptive immunity is the ability of the body to specifically counteract foreign organisms or substances called antigens.
Adaptive immunity results from production of specialized lymphocytes and antibodies.
Humoral (Antibody-Mediated) Immunity
Found in body fluids.
Antibodies made by plasma cells (activated B lymphocytes) in response to specific antigen.
Primarily defends against bacteria, viruses, and toxins in blood and lymph - extracellular antigens.
Cell-Mediated Immunity
T cells have antigen receptors but don’t make antibodies – lyse target cells directly.
Primarily responds against intracellular viruses, multicellular parasites, transplanted tissue and cancer cells